Detalhe da pesquisa
1.
Simultaneous Delivery of Doxorubicin and Protease Inhibitor Derivative to Solid Tumors via Star-Shaped Polymer Nanomedicines Overcomes P-gp- and STAT3-Mediated Chemoresistance.
Biomacromolecules
; 23(6): 2522-2535, 2022 06 13.
Artigo
Inglês
| MEDLINE | ID: mdl-35584053
2.
Bloodstream Stability Predetermines the Antitumor Efficacy of Micellar Polymer-Doxorubicin Drug Conjugates with pH-Triggered Drug Release.
Mol Pharm
; 15(9): 3654-3663, 2018 09 04.
Artigo
Inglês
| MEDLINE | ID: mdl-29543465
3.
Metastatic spread inhibition of cancer cells through stimuli-sensitive HPMA copolymer-bound actinonin nanomedicines.
Nanomedicine
; 44: 102578, 2022 08.
Artigo
Inglês
| MEDLINE | ID: mdl-35779856
4.
Evaluation of linear versus star-like polymer anti-cancer nanomedicines in mouse models.
J Control Release
; 353: 549-562, 2023 01.
Artigo
Inglês
| MEDLINE | ID: mdl-36470330
5.
Dimerization of an immunoactivating peptide derived from mycobacterial hsp65 using N-hydroxysuccinimide based bifunctional reagents is critical for its antitumor properties.
Bioconjug Chem
; 23(10): 2032-41, 2012 Oct 17.
Artigo
Inglês
| MEDLINE | ID: mdl-22988810
6.
SOT101 induces NK cell cytotoxicity and potentiates antibody-dependent cell cytotoxicity and anti-tumor activity.
Front Immunol
; 13: 989895, 2022.
Artigo
Inglês
| MEDLINE | ID: mdl-36300122
7.
Glycopolymers Decorated with 3-O-Substituted Thiodigalactosides as Potent Multivalent Inhibitors of Galectin-3.
J Med Chem
; 65(5): 3866-3878, 2022 03 10.
Artigo
Inglês
| MEDLINE | ID: mdl-35157467
8.
Antitumor activity of IL-2/anti-IL-2 mAb immunocomplexes exerts synergism with that of N-(2-hydroxypropyl)methacrylamide copolymer-bound doxorubicin conjugate due to its low immunosuppressive activity.
Int J Cancer
; 129(8): 2002-12, 2011 Oct 15.
Artigo
Inglês
| MEDLINE | ID: mdl-21165950
9.
HPMA-Based Copolymers Carrying STAT3 Inhibitor Cucurbitacin-D as Stimulus-Sensitive Nanomedicines for Oncotherapy.
Pharmaceutics
; 13(2)2021 Jan 28.
Artigo
Inglês
| MEDLINE | ID: mdl-33525658
10.
Polymer-ritonavir derivate nanomedicine with pH-sensitive activation possesses potent anti-tumor activity in vivo via inhibition of proteasome and STAT3 signaling.
J Control Release
; 332: 563-580, 2021 04 10.
Artigo
Inglês
| MEDLINE | ID: mdl-33722611
11.
HPMA copolymer conjugates of paclitaxel and docetaxel with pH-controlled drug release.
Mol Pharm
; 7(4): 1015-26, 2010 Aug 02.
Artigo
Inglês
| MEDLINE | ID: mdl-20518512
12.
Preclinical evaluation of linear HPMA-doxorubicin conjugates with pH-sensitive drug release: efficacy, safety, and immunomodulating activity in murine model.
Pharm Res
; 27(1): 200-8, 2010 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-19894105
13.
Polymer nanomedicines based on micelle-forming amphiphilic or water-soluble polymer-doxorubicin conjugates: Comparative study of in vitro and in vivo properties related to the polymer carrier structure, composition, and hydrodynamic properties.
J Control Release
; 321: 718-733, 2020 05 10.
Artigo
Inglês
| MEDLINE | ID: mdl-32142741
14.
HPMA-based star polymer biomaterials with tuneable structure and biodegradability tailored for advanced drug delivery to solid tumours.
Biomaterials
; 235: 119728, 2020 03.
Artigo
Inglês
| MEDLINE | ID: mdl-32044514
15.
Micelle-Forming Block Copolymers Tailored for Inhibition of P-gp-Mediated Multidrug Resistance: Structure to Activity Relationship.
Pharmaceutics
; 11(11)2019 Nov 05.
Artigo
Inglês
| MEDLINE | ID: mdl-31694350
16.
Polymer donors of nitric oxide improve the treatment of experimental solid tumours with nanosized polymer therapeutics.
J Drug Target
; 25(9-10): 796-808, 2017.
Artigo
Inglês
| MEDLINE | ID: mdl-28726521
17.
The structure of polymer carriers controls the efficacy of the experimental combination treatment of tumors with HPMA copolymer conjugates carrying doxorubicin and docetaxel.
J Control Release
; 246: 1-11, 2017 01 28.
Artigo
Inglês
| MEDLINE | ID: mdl-27940304
18.
Tumor-targeted micelle-forming block copolymers for overcoming of multidrug resistance.
J Control Release
; 245: 41-51, 2017 01 10.
Artigo
Inglês
| MEDLINE | ID: mdl-27871991
19.
Properties of HPMA copolymer-doxorubicin conjugates with pH-controlled activation: effect of polymer chain modification.
J Control Release
; 115(1): 26-36, 2006 Sep 28.
Artigo
Inglês
| MEDLINE | ID: mdl-16899320
20.
The structure-dependent toxicity, pharmacokinetics and anti-tumour activity of HPMA copolymer conjugates in the treatment of solid tumours and leukaemia.
J Control Release
; 223: 1-10, 2016 Feb 10.
Artigo
Inglês
| MEDLINE | ID: mdl-26708020